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Image Search Results
Journal: Frontiers in Immunology
Article Title: A Systems Biology Approach Identifies B Cell Maturation Antigen (BCMA) as a Biomarker Reflecting Oral Vaccine Induced IgA Antibody Responses in Humans
doi: 10.3389/fimmu.2021.647873
Figure Lengend Snippet: BCMA responses in ALS specimens correlate with Dukoral® ALS vaccine responses in Swedish volunteers. (A) Concentrations of BCMA (pg/mL) in ALS specimens were quantified by ELISA in 29 individuals before (pre) and after (post) primary and booster Dukoral® vaccination. Horizonal bars represent geometric mean values. (B) Correlation between the magnitudes of ALS CTB IgA responses and ALS BCMA fold rises following primary and booster Dukoral® vaccinations. (C) Correlation between the magnitudes of ALS OSP IgA and ALS BCMA responses following primary and booster Dukoral® vaccinations. Each symbol represents one individual.
Article Snippet: For
Techniques: Enzyme-linked Immunosorbent Assay
Journal: International Journal of Molecular Sciences
Article Title: The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG
doi: 10.3390/ijms22062938
Figure Lengend Snippet: Assessing if dual DFX-bedaquiline treatment affects chemokine secretions in BCG-infected hMDMs. hMDMs, obtained from healthy blood donors, were infected with BCG for three hours and were subsequently treated with DFX (100 µM) in combination with bedaquiline (0.5 µg/mL). Twenty-four hours post BCG infection, cell supernatants were collected and levels of ( A ) eotaxin, ( B ) eotaxin-3, ( C ) TARC, ( D ) IP-10, ( E ) MCP-1, ( F ) MCP-4, ( G ) MDC, ( H ) MIP-1α and ( I ) MIP-1β were quantified using Meso Scale Discovery Multi-Array technology ( n = 5). Bars denote mean ± SEM. p > 0.05 (Two-way repeated measures ANOVA tests with Šídák’s multiple comparisons tests).
Article Snippet:
Techniques: Infection